Biophysics - Latest publications đź“„

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Somex lab was part of two recent publications focused on cancer research and development of a tutorial on Myxococcus xanthus.

Publication 1:

De Novo Gene Transcription of Connexin Mediates Cytoplasmic Fluid Exchange and Flocking Transitions in Physiological and Cancerous Epithelial Systems

This study explores how connexin transcription and gap-junction communication drive fluid-like transitions and collective cell migration in epithelial tissues. Our students Jasmin and Fabian employed PIV (Particle Image Velocimetry) analysis to measure the coordinated and ordered cell motions across the monolayers. In particular, correlation length and order parameter show a remarkable increase in the presence of epidermal growth factor, reflecting the collective alignment of cells.

Links:


Publication 2:

Myxococcus xanthus for active matter studies: a tutorial for its growth and potential applications

This tutorial provides a detailed, practical guide for cultivating, developing, and preparing experimental samples of M. xanthus. The tutorial also highlights several benchmark experiments—motility assays, fruiting body formation, predation, and elasticotaxis—all of which showcase how this organism can be used to explore the fundamentals of collective motion and emergent mechanics.

Our PhD student Jasmin and intern student David contributed by validating the protocols established in the tutorial.

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Roberto Cerbino
Roberto Cerbino
Professor of Experimental Soft Matter Physics

My research interests include Soft matter physics, living matter, cell biophysics and quantitative microscopy.

Jasmin Di Franco
Jasmin Di Franco
PhD Student

My research interests include Cell biophysics, Living matter and Soft matter physics.

Fabian Krautgasser
Fabian Krautgasser
MSc Student

My research interests include structure & dynamics of cellular monolayers, data analysis & visualisation in Python.

David Steiner
David Steiner
MSc Student
📢 Roberto joins PCIG! 🎉 Congratulations New Job 🚨 New Project alert 📄 Latest publication: ShearView 📢 Roberto joins PCIG! 🎉 Congratulations New Job 🚨 New Project alert 📄 Latest publication: ShearView